The sequence of the target DNA itself can affect PCR efficiency. The GC-rich sequences in target DNA may form secondary structures in the single strands produced by denaturation; this could reduce PCR efficiency.

TLS Online TPP Program

#Id: 7239

#Unit 5. Developmental Biology

B cell properties 

They are APCs

They can express MHC2

Have surface marker  CD19

Antibodies at surface of b cell – IgM, IgD

Part of Adaptive immunity 

B cell convert into plasma cell

TLS Online TPP Program

#Id: 7240

#Unit 5. Developmental Biology

Surface protein on B cell

CR2(CR21)

CD19

TAPA-1(CD81)

mIg 

Igα/ Igβ

(CD79a and CD79B)

TLR

CD40

B7 (CD80/86)

ICAM-1

MHC-1 and 2

CD 22

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#Id: 7241

#Unit 5. Developmental Biology

Formation of mature B-cell

TLS Online TPP Program

#Id: 7242

#Unit 5. Developmental Biology

Progress through their developmental program

TLS Online TPP Program

#Id: 7243

#Unit 5. Developmental Biology

TLS Online TPP Program

#Id: 7244

#Unit 5. Developmental Biology

B-Cell Development