End-labelling of a gene probe at the 5′ end with alkaline phosphatase and polynucleotide kinase. 

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#Id: 8583

#Unit 2. Cellular Organization

Lamins 

contribute to genome organization as well as to the rigidity of the nucleus through linkages to the

cytoskeleton involving proteins with SUN and KASH domains

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#Id: 8584

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8585

#Unit 2. Cellular Organization

Emerin

lamin-binding membrane protein of the inner nuclear envelope

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#Id: 8586

#Unit 2. Cellular Organization

Inside the nucleus, SUN proteins bind to the nuclear lamina or chromosomes.

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#Id: 8587

#Unit 2. Cellular Organization

In the cytoplasm, KASH proteins can bind directly to microfilaments and indirectly to microtubules and Ifs through association with motor proteins and plakins, respectively.

TLS Online TPP Program

#Id: 8588

#Unit 2. Cellular Organization