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Lane 3 depicts the behavior of the same DNA bound to two proteins. The mobility is reduced still further because of the greater mass of protein clinging to the DNA. This is 

called a supershift. 




#Unit 13. Methods in Biology #DNA sequencing methods- Gel Mobility Shift #Part B Pointers
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TLS Online TPP Program

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#Unit 2. Cellular Organization

Interphase chromatin is a mass occupying a large part of the nuclear volume


TLS Online TPP Program

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#Unit 2. Cellular Organization

Mitotic chromosomes are highly organized and reproducible ultrastructure

TLS Online TPP Program

#Id: 482

#Unit 2. Cellular Organization

Interphase chromatin remain attached to nuclear wall proteins via matrix attachment regions (MARs) or matrix attachment DNA sequences

TLS Online TPP Program

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#Unit 2. Cellular Organization

Interphase chromosomes occupy chromosome territories in the nucleus and are not entangled with each other


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#Unit 2. Cellular Organization

Heterochromatic regions, silenced genes, and gene-sparse regions of chromosomes are typically localized to the nuclear periphery.


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#Unit 2. Cellular Organization

Active genes/euchromatin are often found at the borders of chromosome territories, and active genes from several chromosomes may cluster in inter-chromosomal territories that are enriched in transcription machinery.

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