Footprinting is a means of finding the target DNA sequence, or binding site, of a DNA-binding protein.

TLS Online TPP Program

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#Unit 3. Fundamental Processes

One other region behaves like oriC:

The promoter of the dnaA gene also shows a delay before remethylation begins.

While it is hemimethylated, the dnaA promoter is repressed, which causes a reduction in the level of DnaA protein.

So Initiation of Replication (E.coli) takes place when GATC at origin is full methylated as well as promoter of DnaA gene. 

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#Id: 10472

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 2950

#Unit 3. Fundamental Processes

An ARS element consists of an A-T-rich region that contains discrete sites in which mutations affect origin function.

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#Id: 1841

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 7184

#Unit 5. Developmental Biology

Antisense morpholinos to eliminate three BMP antagonists (Noggin, Chordin, and Follistatin) in Xenopus. The resulting embryos had catastrophic failure of dorsal development and lacked neural plates and dorsal mesoderm