DMS footprinting follows a similar principle, except that we use the DNA methylating agent DMS, instead of DNase, to attack the DNA–protein complex. 

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

The Major Pathways of Complement Activation

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Classical Pathway

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Lectin pathway

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Alternative pathway

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Alternative Properdin-Activated Pathway

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

The Alternative Protease-Activated Pathway

Thrombin, could cleave the complement components C3 and C5.