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TLS Online TPP Program

#Id: 3017

All DNA polymerases require a 3'-0H priming end to initiate DNA synthesis.


#Unit 3. Fundamental Processes #Unit of replication and enzymes involved #Part B Pointers
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TLS Online TPP Program

#Id: 10009

#Unit 4. Cell Communication and Cell Signaling

Secretion requires the addition of cholesterol and palmitic acid to the Hedgehog protein
TLS Online TPP Program

#Id: 10010

#Unit 4. Cell Communication and Cell Signaling

Two membrane proteins, 
Smoothened (Smo) 
Patched (Ptc)
TLS Online TPP Program

#Id: 10011

#Unit 4. Cell Communication and Cell Signaling

Smo has seven TM α helices, is a member of the GPCR superfamily, and is related in sequence to the Fz.
TLS Online TPP Program

#Id: 10012

#Unit 4. Cell Communication and Cell Signaling

Ptc contains 12 TM α helices and structurally similar
to the Niemann-Pick C1 protein, a cholesterol transporting member of the ABC superfamily
TLS Online TPP Program

#Id: 10013

#Unit 4. Cell Communication and Cell Signaling

In the absence of Hh,
Ptc inhibits Smoothened and then degraded in proteasomes
TLS Online TPP Program

#Id: 10014

#Unit 4. Cell Communication and Cell Signaling

Transcription Factor
zinc-finger transcription factor Cubitis interruptus