FENl is an exo-jendonuclease that recognizes the structure created when one strand of DNA is displaced from a duplex as a "flap." In mammalian replication it cleaves at the base of the flap to remove the RNA primer.

TLS Online TPP Program

#Id: 590

#Unit 2. Cellular Organization

Virulent phage replicate and kill their host by lysing but Temperate phage such as l, infect cells but don’t necessarily kill.

TLS Online TPP Program

#Id: 591

#Unit 2. Cellular Organization

Lambda phage chooses fate of lytic cycle under stress such as DNA damage 

TLS Online TPP Program

#Id: 592

#Unit 2. Cellular Organization

Genetic Map of Phage l The genome is 48,514 bp

TLS Online TPP Program

#Id: 593

#Unit 2. Cellular Organization

Lytic growth proceeds when PL and PR remain switched on while PRM is kept off. Lysogenic growth, in contrast, is a consequence of PL and PR being switched off and PRM switched on.

TLS Online TPP Program

#Id: 594

#Unit 2. Cellular Organization

cI maintains lysogeny and cro cause lytic cycle

TLS Online TPP Program

#Id: 595

#Unit 2. Cellular Organization

How cro cause lytic cycle- proteolytic cleavage of lambda repressor