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Adenine and guanine are also subject to spontaneous deamination. Deamination converts adenine to hypoxanthine, which hydrogen-bonds to cytosine rather than to thymine; guanine is converted to xanthine,
which continues to pair with cytosine, although with only two hydrogen bonds.

#Unit 3. Fundamental Processes #DNA damage and repair mechanisms #Part B Pointers
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#Unit 7. System Physiology – Animal

Thyroid gland is composed of large numbers of closed follicles & concerned with the production of thyroid hormone





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#Unit 7. System Physiology – Animal

Each spherical follicle is surrounded by a single layer of polarized epithelial cells and filled with pink-staining proteinaceous material called colloid.



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#Unit 7. System Physiology – Animal

Colloid consists predominantly of the glycoprotein, thyroglobulin



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#Unit 7. System Physiology – Animal

The primary hormone secreted by the thyroid is thyroxine (T4) along with much lesser amounts of triiodothyronine (T3)



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#Unit 7. System Physiology – Animal

Basolateral membranes of thyrocytes contain a symporter Na+/I –symporter (NIS) 

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#Unit 7. System Physiology – Animal

Process of concentrating the iodide in the cell is called iodide trapping





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