n BER,  An AP endonuclease cleaves the phosphodiester backbone near the AP site

TLS Online TPP Program

#Id: 5822

#Unit 7. System Physiology – Animal

Angiotensin II stimulates the synthesis and secretion of aldosterone by the activation of phospholipase C via Gq

TLS Online TPP Program

#Id: 5823

#Unit 7. System Physiology – Animal

Important effect of cortisol, Decrease translocation of GLUT4 to the cell membrane

TLS Online TPP Program

#Id: 5824

#Unit 7. System Physiology – Animal

Cortisol induces the synthesis of lipocortin, an inhibitor of the enzyme PLA2.

TLS Online TPP Program

#Id: 5825

#Unit 7. System Physiology – Animal

Cortisol inhibits the production of interleukin-2 and the proliferation of T lymphocytes.

TLS Online TPP Program

#Id: 5826

#Unit 7. System Physiology – Animal

Addison disease (primary adrenocortical insufficiency) caused by autoimmune destruction of all zones of the adrenal cortex.

TLS Online TPP Program

#Id: 5827

#Unit 7. System Physiology – Animal

Cushing syndrome Chronic excess of glucocorticoids (hypersecretion of ACTH from a pituitary adenoma)