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Cells possessing a mutant Pol h are hindered in their ability to bypass thymine dimers during replication and must resort to using another translesion polymerase for bypass to avoid a block in replication. 

#Unit 3. Fundamental Processes #DNA damage and repair mechanisms #Part B Pointers
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#Id: 8863

#Unit 2. Cellular Organization

Defects of cohesin’s gene expression regulation function are the cause of a group of diseases collectively called cohesinopathies.


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#Id: 5101

#Unit 6. System Physiology – Plant

When the CCA1 gene is mutated so that no functional protein is produced, circadian and phytochrome regulation of four genes, including LHCB, is affected.


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#Id: 1383

#Unit 4. Cell Communication and Cell Signaling

Formin protein nucleate the assembly of unbranched filaments, (FH1 and FH2 domains-Actin nucleation by the formin FH2 domain).
Formins are activated by membrane-bound Rho-GTP, a Ras-related small GTPase.
The Arp2/3 Complex Nucleates Branched Filament Assembly.

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#Id: 10146

#Unit 6. System Physiology – Plant

According to the starch–statolith hypothesis, columella of the root cap cells represent statocytes, or gravity-sensing cells

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#Id: 2365

#Unit 5. Developmental Biology

Sigma neoblasts are highly proliferative and are the only stem cells directly responsive to injury.


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