Genes that share a common ancestry have similar organizations with conservation of the positions of the introns.

TLS Online TPP Program

#Id: 5819

#Unit 7. System Physiology – Animal

The renal epithelial cells express the enzyme 11β-HSD2, which prevent cortisol from activating mineralocorticoid receptors.

TLS Online TPP Program

#Id: 5820

#Unit 7. System Physiology – Animal

Apparent mineralocorticoid excess (AME)

11β-hydroxysteroid dehydrogenase type 2 is inhibited or absent

TLS Online TPP Program

#Id: 5821

#Unit 7. System Physiology – Animal

ACTH stimulates the synthesis and secretion of cortisol by the activation of adenylyl cyclase via Gs.

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#Id: 5822

#Unit 7. System Physiology – Animal

Angiotensin II stimulates the synthesis and secretion of aldosterone by the activation of phospholipase C via Gq

TLS Online TPP Program

#Id: 5823

#Unit 7. System Physiology – Animal

Important effect of cortisol, Decrease translocation of GLUT4 to the cell membrane

TLS Online TPP Program

#Id: 5824

#Unit 7. System Physiology – Animal

Cortisol induces the synthesis of lipocortin, an inhibitor of the enzyme PLA2.