The reaction catalyzed by citrate synthase is essentially a Claisen condensation, involving a thioester (acetyl-CoA) and a ketone (oxaloacetate)

TLS Online TPP Program

#Id: 346

#Unit 1. Molecules and their Interaction Relevant to Biology

Pyruvate Carboxylase

a mitochondrial enzyme that requires the coenzyme biotin, converts the pyruvate to oxaloacetate

TLS Online TPP Program

#Id: 7686

#Unit 1. Molecules and their Interaction Relevant to Biology

                                                                        Helix-turn-Helix

Two helices are connected by a small loop or turn

These helices are stabilized by non-polar contacts between the helices

Mostly found in DNA binding proteins, directly involved in DNA binding

Generally consists of 20 amino acids

Second helix is involved in DNA binding, enters in major groove of the target site

TLS Online TPP Program

#Id: 1623

#Unit 4. Cell Communication and Cell Signaling

Defensins (α and β) Disrupt membranes of bacteria, fungi, protozoan.

TLS Online TPP Program

#Id: 3026

#Unit 3. Fundamental Processes

Priming activity is required to provide 3'-0H ends to start off the DNA chains on both the leading and lagging strands.

TLS Online TPP Program

#Id: 6157

#Unit 3. Fundamental Processes