Mutations that remove the 2'-OH of the A residue at the 3' end of the P-site tRNA result in a 10⁶ -fold reduction in catalysis rates.

TLS Online TPP Program

#Id: 7010

#Unit 5. Developmental Biology

Precise control of the division and differentiation of stem cell types is necessary for building the embryo as well as maintaining and regenerating tissues in the adult. progenitor differentiation through endocrine, paracrine, or juxtacrine mechanisms.

TLS Online TPP Program

#Id: 7011

#Unit 5. Developmental Biology

Regulation is highly influenced by the microenvironment that surrounds a stem cell and is known as the stem cell niche.

TLS Online TPP Program

#Id: 7012

#Unit 5. Developmental Biology

All tissue types possess a unique stem cell niche, and despite many differences among the niche architecture of different tissues

TLS Online TPP Program

#Id: 7013

#Unit 5. Developmental Biology

All tissue types possess a unique stem cell niche, and despite many differences among the niche architecture of different tissues.

TLS Online TPP Program

#Id: 7014

#Unit 5. Developmental Biology

The types of the intracellular mechanisms used by a given stem cell are in part the downstream net result of the extracellular stimuli in its niche.

TLS Online TPP Program

#Id: 7015

#Unit 5. Developmental Biology

Physical mechanisms of influence, including Structural & adhesion factors within the extracellular matrix that support the cellular architecture of the niche.