TLS Online TPP Program

#Id: 1467

#Unit 4. Cell Communication and Cell Signaling

Epithelial-to-mesenchymal transition is associated with a reduction in the expression of E-cadherin.

TLS Online TPP Program

#Id: 6708

#Unit 3. Fundamental Processes

Conversion of specific uridine residues to pseudouridine and the addition of methyl groups to the 2′-hydroxyl groups

of specific riboses, that are important for the proper assembly and function of snRNPs in pre-mRNA splicing. 

These modifications occur in Cajal bodies, where they are directed by a class of snoRNA-like guide RNA molecules called scaRNAs (small Cajal body–associated RNAs)

TLS Online TPP Program

#Id: 5340

#Unit 7. System Physiology – Animal

The Frank-Starling law of the heart states that 

The volume of blood ejected by the ventricle depends on the volume present in the ventricle at the end of diastole. The volume present at the end of diastole depends on the volume returned to the heart, or the venous return.

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#Id: 4668

#Unit 13. Methods in Biology

If the antibody preparation is polyclonal and has a range of affinities, Scatchard plot yields a curved line whose slope is constantly changing. The average affinity constant K0 can be calculated by determining the value of Ka when half of the binding sites are occupied (i.e., when r  1 in this example). In this graph, antiserum #3 has a higher affinity (K0  2.4  108) than antiserum #4 (K0  1.25  108)

TLS Online TPP Program

#Id: 10322

#Unit 4. Cell Communication and Cell Signaling

Sometimes the tumor cells up-regulate the expression of anti-apoptotic proteins like BCL-2.