The human type II topoisomerases are targeted by doxorubicin (Adriamycin), etoposide (Etopophos), and ellipticine.

Most of these drugs stabilize the covalent topoisomerase-DNA (cleaved) complex.

TLS Online TPP Program

#Id: 3141

#Unit 7. System Physiology – Animal

Inspiratory reserve volume the extra volume of air that can be inspired over and above the normal tidal volume when the person Inspires with full force

TLS Online TPP Program

#Id: 4707

#Unit 13. Methods in Biology

From the four possible transitions (n!p*, p!p*, n!s*, s!s*), only two can be elicited with light from the UV/Vis spectrum for some biological molecules: n!p* and p!p*. The n!s* and s!s* transitions are

energetically not within the range of UV/Vis spectroscopy and require higher energies.

TLS Online TPP Program

#Id: 6900

#Unit 3. Fundamental Processes

5-hydroxymethylcytosine (5hmC) is now novel epigenetic marks. The “teneleven traProteins that normally recognize 5mC, such as MeCP2, do not bind to 5hmC, suggesting that generation of 5hmC might serve to reverse methylation-dependent silencing.

TLS Online TPP Program

#Id: 8066

#Unit 13. Methods in Biology

Optically active chiral molecules will preferentially absorb one direction of the circularly polarized light. 

TLS Online TPP Program

#Id: 8302

#Unit 1. Molecules and their Interaction Relevant to Biology