The H2A variants are the largest and most diverse family of core histone variants.

TLS Online TPP Program

#Id: 8161

#Unit 2. Cellular Organization

KKXX sorting signal,

binds to a complex of the COPI α and β subunits

TLS Online TPP Program

#Id: 8162

#Unit 2. Cellular Organization

For selective export of certain membrane proteins from the ER contain a di-acidic sorting signal (Asp-X-Glu, or DXE), which binds to the Sec24 subunit of the COPII

TLS Online TPP Program

#Id: 8163

#Unit 2. Cellular Organization

Vesicles coated with AP1 and clathrin bind to  proteins containing a Tyr-X-X-Φ sequence

TLS Online TPP Program

#Id: 8164

#Unit 2. Cellular Organization

Vesicles coated with GGA proteins and clathrin bind to proteins containing 

Asp-X-Leu-Leu and Asp-Phe-Gly-X-Φ sequences

TLS Online TPP Program

#Id: 8165

#Unit 2. Cellular Organization

TANGO1 is an ER membrane protein that acts as a cargo receptor for collagen.

TLS Online TPP Program

#Id: 8166

#Unit 2. Cellular Organization

CFTR protein contains

a di-acidic sorting signal that binds to the Sec24 subunit

of the COPII vesicle coat and is necessary for transport of

the CFTR protein out of the ER.