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TLS Online TPP Program

#Id: 424

30 nm compacts the DNA 40-fold. This structure of this fiber requires the histone tails and is stabilized by linker histones.

#Unit 2. Cellular Organization #Octamer & Nucleosome #Part B Pointers
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TLS Online TPP Program

#Id: 444

#Unit 2. Cellular Organization

The high-mobility group (HMG) are nonhistones and may contain Transcriptional Factors.
TLS Online TPP Program

#Id: 445

#Unit 2. Cellular Organization

Core DNA has an invariant length of 146 bp, the minimum length of DNA needed to form a stable monomeric nucleosome, and is relatively resistant to digestion by nucleases- DNA FINGER PRINTING
TLS Online TPP Program

#Id: 446

#Unit 2. Cellular Organization

Linker DNA comprises the rest of the repeating unit. Its length varies from as little as 8 bp to as many as 114 bp per nucleosome.
TLS Online TPP Program

#Id: 447

#Unit 2. Cellular Organization

The predicted mass of the nucleosome is 262 kD.
TLS Online TPP Program

#Id: 448

#Unit 2. Cellular Organization

The nucleosome consists of approximately equal masses of DNA and histones (including H1).
TLS Online TPP Program

#Id: 449

#Unit 2. Cellular Organization

H32-H42 tetramer accounts for the diameter of the octamer. It forms the shape of a horseshoe.