Collaborative gene interaction

TLS Online TPP Program

#Id: 5042

#Unit 3. Fundamental Processes

Before replication, the palindromic target GATC site is methylated by dam methylase on the N6 of A of each strand.

Replication generates hemimethylated DNA, in which one strand is methylated and one strand is unmethylated.

Thus, the replication event converts Dam target sites from fully methylated to hemimethylated condition.

TLS Online TPP Program

#Id: 10384

#Unit 4. Cell Communication and Cell Signaling

Class II MHC transcriptional activator called CIITA and another transcription factor called RFX, have both been shown to activate the promoter of class II MHC genes.

Defects in these transcription factors cause one form of bare lymphocyte syndrome.

TLS Online TPP Program

#Id: 3706

#Unit 2. Cellular Organization

When a genome contains a cluster of genes with related sequences, mispairing between nonallelic loci can cause unequal crossing over. This produces a deletion in one recombinant chromosome and a corresponding duplication in the other.

TLS Online TPP Program

#Id: 9918

#Unit 4. Cell Communication and Cell Signaling

Innate response elements commonly engaged by encounter with viral PAMPs, such as secretion of type I interferons, inflammasome and NK-cell activation, as well as IL-12 production.

TLS Online TPP Program

#Id: 2824

#Unit 13. Methods in Biology

Ion exchangers often use Gradient elution than isocratic elution, while Gradient elution is based on gradient of pH and ionic strength.