Plasminogen is converted to active plasmin when t-PA hydrolyzes the bond between Arg 560 and Val 561. plasmin also activated by urokinase-type plasminogen activator (u-PA).

TLS Online TPP Program

#Id: 3523

#Unit 2. Cellular Organization

Pseudogenes arise from the action of an enzyme called reverse transcriptase

TLS Online TPP Program

#Id: 3524

#Unit 2. Cellular Organization

The coexistence of multiple alleles at a locus in a population is called genetic polymorphism. A locus is usually defined as polymorphic if two or more alleles are present at a frequency of more than 1% in the population.

TLS Online TPP Program

#Id: 3525

#Unit 2. Cellular Organization

On average, one SNP occurs for approximately every 1330 bases in the human genome means 1 million SNP/genome

TLS Online TPP Program

#Id: 3526

#Unit 2. Cellular Organization

A point mutation that affects a restriction site is detected by a difference in restriction fragment lengths.

TLS Online TPP Program

#Id: 3527

#Unit 2. Cellular Organization

RFLPs and SNPs can be the basis for linkage maps and are useful for establishing parent–offspring relationships.

TLS Online TPP Program

#Id: 3528

#Unit 2. Cellular Organization

Sections of DNA that are conserved among species can be identified by performing a zoo blot. We use short fragments from the region as labeled probes to test for homologous DNA from a variety of species by Southern blotting.