Nurturing Life Sciences
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#Unit 5. Developmental Biology
The mRNA for the transcription factor VegT, which becomes apportioned to the vegetal cells during cleavage. VegT is critical in generating both the endodermal and mesodermal lineages.
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One of the genes activated by VegT protein encodes the Sox17 transcription factor.
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Sox17
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Another set of early genes activated by VegT encodes Nodal paracrine factors that instruct the cell layers above them to become mesoderm
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Nieuwkoop center
Dorsalmost vegetal cells of the blastula, which are capable of inducing the organizer dorsal vegetal cells can induce animal cells to become dorsal mesodermal tissue)