The thick ascending limb of the loop of Henle is the site of action of the powerful “loop” diuretics such as

Furosemide

Ethacrynic acid

Bumetanide 

TLS Online TPP Program

#Id: 659

#Unit 3. Fundamental Processes

Telomeric sequence is the extension of the G-T–rich strand, which for 14 to 16 bases is usually a single strand.

TLS Online TPP Program

#Id: 6543

#Unit 7. System Physiology – Animal

In resting cells, virtually all of the GLUT4 is localized to small vesicles in the cytosol While some GLUT4 is in endosomes, most is in a unique small organelle termed the GLUT4 storage vesicle (GSV)

TLS Online TPP Program

#Id: 5888

#Unit 3. Fundamental Processes

Incorrect base pairing leads to dramatically lower rates of nucleotide addition as a result of a catalytically unfavorable alignment of these substrates. This is an example of kinetic proofreading, in which an enzyme favors catalysis using one of several possible substrates by dramatically increasing the rate of bond formation only when the correct substrate is present. 

TLS Online TPP Program

#Id: 8883

#Unit 2. Cellular Organization

Once mitotic CDKs are activated at the end of G2 , they phosphorylate specific serine residues in all 3 nuclear lamins.

TLS Online TPP Program

#Id: 5386

#Unit 10. Ecological Principles

Density-independent factors limit population size regardless of the population’s density.

Common density-independent factors include natural disasters such as tornadoes, hurricanes, floods, and fires.