The principal cells are the primary sites of action of the potassium-sparing diuretics, including spironolactone, eplerenone, amiloride, and triamterene

TLS Online TPP Program

#Id: 3022

#Unit 3. Fundamental Processes

DnaB is the helicase that unwinds DNA for replication in E.coli.

TLS Online TPP Program

#Id: 3023

#Unit 3. Fundamental Processes

DNA polymerases cannot initiate DNA synthesis on duplex or single-stranded DNA without a primer.

TLS Online TPP Program

#Id: 3024

#Unit 3. Fundamental Processes

 DnaB is the helicase that unwinds DNA for replication in E.coli.

TLS Online TPP Program

#Id: 3025

#Unit 3. Fundamental Processes

A preformed RNA (often a tRNA) pairs with the template, allowing its 3'-0H end to be used to prime DNA synthesis.

TLS Online TPP Program

#Id: 3026

#Unit 3. Fundamental Processes

Priming activity is required to provide 3'-0H ends to start off the DNA chains on both the leading and lagging strands.

TLS Online TPP Program

#Id: 3027

#Unit 3. Fundamental Processes

Each Okazaki fragment starts with a primer sequence of RNA - 10 bases long that provides the 3'-0H end for extension by DNA polymerase.