Ecotypes, individuals of a species that vary in external appearance and their variations are genetically fixed and irreversible The individuals of a species growing under different environmental conditions differ in external appearance, but these changes are only temporary, not permanent, and hence reversible Ecads (Ecophenes). 

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#Unit 2. Cellular Organization

In mammalian cells, Rab5 protein (early endosomes) and its effector protein known as EEA1 (early endosome antigen 1)

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#Unit 2. Cellular Organization

Effector proteins of Rab6 is Kinesin

Effector proteins of Rab27 is Type V Myosin

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#Unit 2. Cellular Organization

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#Unit 2. Cellular Organization

Sets of SNARE Proteins responsible for the eventual fusion of a vesicle with the target membrane:

Vesicle-specific membrane protein, v-SNARE

Target membrane contains t-SNARE

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#Unit 2. Cellular Organization

SNARE-mediated fusion occurs during exocytosis of secreted proteins. In this case, 

v-SNARE, are VAMP 

t-SNAREs are syntaxin & SNAP-25

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#Unit 2. Cellular Organization

SNARE complex is disassembled by ATP-dependent reaction mediated by cytosolic proteins, NSF & α-SNAP