Nurturing Life Sciences
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#Unit 4. Cell Communication and Cell Signaling
The heavy chain is then expressed on the cell surface in combination with the surrogate light chain, which is made up of VpreB and λ5.
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BAFF-R expression is first detected in T1 B cells and increases steadily there after.
Signaling through the BAFF/BAFF-R axis promotes survival of transitional B cells by inducing the synthesis of anti-apoptotic factors such as Bcl-2, Bcl-xl, and Mcl-1