TLS Online TPP Program

#Id: 8377

#Unit 2. Cellular Organization

Myosins have 

Motor head domain

Lever-arm neck domain

Cargo-binding tail domain

TLS Online TPP Program

#Id: 8378

#Unit 2. Cellular Organization

The first myosin discovered

Myosin II, was isolated from skeletal muscle.

TLS Online TPP Program

#Id: 8379

#Unit 2. Cellular Organization

Three classes of myosins:

Myosin I

Myosin II

Myosin V

TLS Online TPP Program

#Id: 8380

#Unit 2. Cellular Organization

single head domain

Function- Membrane association, endocytosis

TLS Online TPP Program

#Id: 8381

#Unit 2. Cellular Organization

Myosin II

Two heads and assembles into bipolar filaments

Small and non-processive

Function- Contraction

TLS Online TPP Program

#Id: 8382

#Unit 2. Cellular Organization

Myosin V

Two heads but does not assemble into filaments

Large and processive

Function- Organelle transport