In mammalian cells, Cdc6 is controlled differently; it is phosphorylated during S phase, and as a result it is degraded by the ubiquitination pathway.  Cdt1 is initially stabilized by the protein Geminin, which prevents its degradation, and subsequent Geminin binding prevents its reuse

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#Id: 10271

#Unit 6. System Physiology – Plant

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#Id: 9676

#Unit 4. Cell Communication and Cell Signaling

Phosphorylation by the mTORC2 kinase complex, of a second serine on

PKB that is not in the activation loop is necessary for maximal PKB activity

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#Id: 981

#Unit 5. Developmental Biology

Brain formation requires,  inhibiting both the Wnt and  BMP pathways.

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#Id: 6992

#Unit 5. Developmental Biology

Unipotency

A unipotent cell that one stem cell has the capacity to differentiate into one cell type Eg- spermatogonia

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#Id: 7213

#Unit 5. Developmental Biology

Class I presentation requires internal synthesis of virus protein, as shown by the requirement that the target cell be infected by live virus, and by the inhibition of class I presentation observed when protein synthesis was blocked by the inhibitor emetine