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However, these mutations also interfere with the synthesis of melanin pigment, lightening the color of the hair; therefore, individuals with PKU frequently have light brown or blond hair.

#Unit 8. Inheritance Biology #Extensions of Mendelism #Part B Pointers
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#Unit 2. Cellular Organization

For selective export of certain membrane proteins from the ER contain a di-acidic sorting signal (Asp-X-Glu, or DXE), which binds to the Sec24 subunit of the COPII

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#Unit 2. Cellular Organization

The Mad1-Mad2 complex bound to a kinetochore adopts the active closed form (Mad2-C) and has the ability to convert inactive open Mad2 (Mad2-O) in the cytoplasm into active closed Mad2 is able to inhibit APC/Ccdc20

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#Unit 2. Cellular Organization

Unfolded-protein response
Key protein –Ire1 promotes formation of Hac1



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#Unit 3. Fundamental Processes

Bacterial replicons are usually circles that replicate bidirectionally from a single origin.

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#Unit 7. System Physiology – Animal

Rapid Ventricular Ejection When ventricular pressure becomes greater than aortic pressure, the aortic valve opens (left heart).

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