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TLS Online TPP Program

#Id: 6309

In hydrolytic editing, the polymerase backtracks by one or more nucleotides and cleaves the RNA product, removing the error-containing sequence. 

#Unit 3. Fundamental Processes #Prokaryotic Transcription #Part B Pointers
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TLS Online TPP Program

#Id: 2948

#Unit 3. Fundamental Processes

Related ORC complexes are found in multicellular eukaryotes.
TLS Online TPP Program

#Id: 2949

#Unit 3. Fundamental Processes

an ARS for autonomously replicating sequence, ARS elements are derived from origins of replication.
TLS Online TPP Program

#Id: 2950

#Unit 3. Fundamental Processes

An ARS element consists of an A-T-rich region that contains discrete sites in which mutations affect origin function.
TLS Online TPP Program

#Id: 2951

#Unit 3. Fundamental Processes

An ARS extends for -so bp and includes a consensus sequence (A} and additional elements (B1-B3).
TLS Online TPP Program

#Id: 2952

#Unit 3. Fundamental Processes

Mutations in three adjacent elements, numbered B 1 to B3, reduce origin function.
TLS Online TPP Program

#Id: 2953

#Unit 3. Fundamental Processes

By counting the number of sites to which ORC binds, we can estimate that there are about 400 origins of replication in the yeast genome.