COPY NUMBER MUTATION are analyzed by simple PCR technique.

#Id: 9245

#Unit 6. System Physiology – Plant

#Id: 6287

#Unit 3. Fundamental Processes

As RNA polymerase moves along the DNA template, it unwinds the duplex at the front of the bubble (the unwinding point), and the DNA  automatically reforms the double helix at the back (the rewinding point).  The length of thetranscription bubble is 12 to 14 bp, but the length of the RNA–DNA hybrid within the bubble is only 8 to 9 bp. As the enzyme moves along the template, the DNA duplex reforms, and the RNA is displaced as a free polynucleotide chain The last 14 ribonucleotides in the growing RNA are complexed with the DNA and/or the enzyme at any given moment.

#Id: 4501

#Unit 13. Methods in Biology

#Id: 2581

#Unit 7. System Physiology – Animal

#Id: 6700

#Unit 3. Fundamental Processes

The introns in pre-tRNA vary in length from 14 to 60 bases and only single intron is found in each pre-tRNA transcript A pre-tRNA intron is excised in one step  Finally, hydrolysis of GTP and ATP is required to join the two tRNA halves generated by cleavage on either side of the intron.