Autosomal dominant 

Traits appear in both sexes with equal frequency.

Both sexes are capable of transmitting these traits to their offspring.

An affected person has an affected parent (unless the person carries new mutations). 

The trait does not skip generations.

Unaffected people do not transmit the trait. 

Example- familial hypercholesterolemia, Huntington disease, Neurofibromatosis

TLS Online TPP Program

#Id: 4537

#Unit 12. Applied Biology

Recombinant vaccines

TLS Online TPP Program

#Id: 4538

#Unit 12. Applied Biology

Subunit vaccines contain only specific protein from a pathogenic organism. For a virus, this protein is often the coat protein.

TLS Online TPP Program

#Id: 4539

#Unit 12. Applied Biology

TLS Online TPP Program

#Id: 4540

#Unit 12. Applied Biology

For subunit vaccine, a eukaryotic cloning host is always used because the recombinant proteins produced by bacteria are nonglycosylated, and glycosylation is necessary for the proteins to be immunologically active.

TLS Online TPP Program

#Id: 4541

#Unit 12. Applied Biology

The first recombinant subunit vaccine approved for use in humans (against hepatitis B) was made in yeast.

TLS Online TPP Program

#Id: 4542

#Unit 12. Applied Biology

DNA vaccines use the DNA of a pathogen to elicit an immune response.