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Lod (logarithm of odds) scores
To determine the probability that genes are actually linked, geneticists often calculate lod (logarithm of odds) scores. 



#Unit 8. Inheritance Biology #Human genetics #Part B Pointers
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#Unit 2. Cellular Organization

Histone tail modifications 


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#Unit 2. Cellular Organization

Bromodomains recognize acetylated lysine.

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#Unit 2. Cellular Organization

The chromodomain is a common protein motif of 60 amino acid that recognizes methylated lysine and Arg. 

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#Unit 2. Cellular Organization

PHD and the Tudor domain also recognizes methyl-lysine.

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#Unit 2. Cellular Organization

Parity rules were given by Erwin Chargaff
I. Rule of complementarity 
II. Rule of Equal amount applies more closely to introns than to exons
III. Cluster rule – Purines in nontemplate strand applies more closely to Exons

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#Unit 2. Cellular Organization

GC Rule- GC content tends to be greater in exons than in introns

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