TLS Online TPP Program

#Id: 6488


TBP causes the minor groove to be widened to an almost flat conformation; it also bends the DNA by an angle of 80. The interaction between TBP and DNA involves only a limited number of hydrogen bonds between the protein and the edges of the base pairs in the minor groove.  Instead, much of the specificity is imposed by two pairs of phenylalanine side chains that intercalate between the base pairs at either end of the recognition sequence and drive the strong bend in the DNA.






#Unit 3. Fundamental Processes #Eukaryotic Transcription #Part B Pointers
More Pointers
TLS Online TPP Program

#Id: 1346

#Unit 4. Cell Communication and Cell Signaling

Post-translational modifications of the CAAX motifs determine the subcellular localization and correct biological function of Ras proteins.

TLS Online TPP Program

#Id: 9297

#Unit 6. System Physiology – Plant

Nitrite reductase
Nitrite (NO2-) is a highly reactive, potentially toxic ion.
Plant cells immediately transport the nitrite into chloroplasts or plastids.
The enzyme nitrite reductase reduces nitrite to ammonium.
Leaf chloroplasts and root plastids contain different forms of nitrite reductase.
Each polypeptide contains two prosthetic groups, an iron-sulfur group and a specialized heme.
NO3-, high sucrose conc, and light induce the transcription of nitrite reductase mRNA.
Asparagine and glutamine repress the induction.

TLS Online TPP Program

#Id: 4689

#Unit 11. Evolution and Behavior

When the fitness interests of two individuals are different, they are in conflict.

The evolution of cooperation and conflict depends on when these kinds of behaviors are favored by natural selection.

TLS Online TPP Program

#Id: 1029

#Unit 5. Developmental Biology

There are two principal modes of neurulation: 
1. Primary neurulation
2. Secondary neurulation

TLS Online TPP Program

#Id: 10567

#Unit 4. Cell Communication and Cell Signaling

Inflammation due to necroptosis has been implicated in mediating major human inflammatory diseases: rheumatoid arthritis, inflammatory bowel disease,
amyotrophic lateral sclerosis, Alzheimer’s disease and progressive atherosclerotic lesions