The influx of Ca2+ ions raises, triggering the fusion of insulin- containing secretory vesicles with the plasma membrane and the secretion of insulin

TLS Online TPP Program

#Id: 2582

#Unit 7. System Physiology – Animal

Late proximal tubule reabsorbs primarily NaCl.

TLS Online TPP Program

#Id: 2583

#Unit 7. System Physiology – Animal

In late proximal convoluted tubule

High tubular fluid Cl− concentration is the driving

force for reabsorption

TLS Online TPP Program

#Id: 2584

#Unit 7. System Physiology – Animal

There are two components for Cl− reabsorption:

Transcellular

Paracellular

TLS Online TPP Program

#Id: 2585

#Unit 7. System Physiology – Animal

Function of the two exchangers is to transport NaCl from the lumen into the cell:

Na+-H+ exchanger

Cl−-formate− anion exchanger

TLS Online TPP Program

#Id: 2586

#Unit 7. System Physiology – Animal

The proximal tubule is an important site for secretion of organic acids and bases such as bile salts, oxalate, urate, and catecholamines.

TLS Online TPP Program

#Id: 2649

#Unit 7. System Physiology – Animal

Thin descending and thin ascending segments, have thin epithelial membranes with no brush borders, few mitochondria, & minimal levels of metabolic activity.