Splice sites are directional in nature. 5’ splice site -the left, or donor, site and the 3’ splice site - right, or acceptor, site

TLS Online TPP Program

#Id: 1470

#Unit 4. Cell Communication and Cell Signaling

A protein called Snail that suppresses the expression of E-cadherin is associated with the epithelial-to-mesenchymal transition.

TLS Online TPP Program

#Id: 1471

#Unit 4. Cell Communication and Cell Signaling

The extracellular matrix is a dynamic, complex meshwork of proteins and polysaccharides that contributes to the structure and function of a tissue. 

TLS Online TPP Program

#Id: 1472

#Unit 4. Cell Communication and Cell Signaling

The major classes of ECM molecules are: 

• Proteoglycans

• Collagens

• Multi-adhesive matrix proteins

 

TLS Online TPP Program

#Id: 1473

#Unit 4. Cell Communication and Cell Signaling

Integrins function as adhesion receptors and CAMs in wide variety of epithelial and nonepithelial cells, mediating cell-matrix and cell-cell interactions.

TLS Online TPP Program

#Id: 1474

#Unit 4. Cell Communication and Cell Signaling

All integrins bind to proteins that consist of tripeptide sequence Arg-Gly-Asp, called the RGD motif

TLS Online TPP Program

#Id: 1555

#Unit 4. Cell Communication and Cell Signaling

Wnts are paracrine factors that make up a large family of cysteine-rich glycoproteins.