TLS Online TPP Program

#Id: 6765


P bodies are dense cytoplasmic domains many times the size of a ribosome. They are sites of translational repression that contain no ribosomes or translation factors. They are also major sites of mRNA degradation in the cytoplasm. Exon-junction complexes upf complex functions in nonsense-mediated decay and induces degradation of the mRNA by P body–associated 5′→3′ exoribonuclease XRN1 



#Unit 3. Fundamental Processes #mRNA stability, transport, CRISPR, miRNA & siRNA #Part B Pointers