Cdc13 is a positive activator of telomerase

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#Unit 13. Methods in Biology

Type I and Type II Errors Example

Null hypothesis- A patient’s signs after treatment A, are the same from a placebo.

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#Unit 13. Methods in Biology

The level of significance is the measurement of the statistical significance.

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#Unit 13. Methods in Biology

level of significance defines whether the null hypothesis is assumed to be accepted or rejected. It is expected to identify if the result is statistically significant for the null hypothesis to be false or rejected.

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#Unit 13. Methods in Biology

The level of significance is denoted by the Greek symbol α (alpha).

Therefore, the level of significance is defined as follows: 

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#Unit 13. Methods in Biology

To measure the level of statistical significance of the result, the investigator first needs to calculate the p-value. It defines the probability of identifying an effect which provides that the null hypothesis is true.

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#Unit 13. Methods in Biology

When the p-value is less than the level of significance (α), the null hypothesis is rejected. If the p-value so observed is not less than the significance level α, then theoretically null hypothesis is accepted.