Heterochromatin formation at telomeres and silent mating-type loci in yeast relies on an overlapping set of genes known as silent information regulators (SIR genes).

TLS Online TPP Program

#Id: 8192

#Unit 2. Cellular Organization

Catalase, are synthesized as precursors with PTS1

Thiolase, are synthesized as precursors with PTS2

TLS Online TPP Program

#Id: 8193

#Unit 2. Cellular Organization

Pex5 forms a multimeric complex with the Pex14 receptor located on the peroxisomal membrane. 

TLS Online TPP Program

#Id: 8194

#Unit 2. Cellular Organization

After assembly of the matrix protein-Pex5-Pex14 complex, the matrix protein dissociates from Pex5 and is released into the peroxisomal matrix.

TLS Online TPP Program

#Id: 8195

#Unit 2. Cellular Organization

A Pex 2, Pex 10, and Pex 12 complex embedded in the peroxisomal membrane transfers Ubiquitin to two embedded Pex 5 receptors.

TLS Online TPP Program

#Id: 8196

#Unit 2. Cellular Organization

The AAA ATPases Pex1 and Pex6 complex use the energy from ATP hydrolysis and causing the detachment of Pex 5 receptors into cytosol.

TLS Online TPP Program

#Id: 8197

#Unit 2. Cellular Organization

Zellweger syndrome

Autosomal recessive Mutations in any of a dozen different peroxins, the most common being Pex1, cause an impairment in peroxisomal protein import.