5-hydroxymethylcytosine (5hmC) is now novel epigenetic marks. The “teneleven translocation 1-3” or Tet1-3 proteinsare DNA TET hydroxylase enzymes that can convert 5mC to 5hmC, and can further convert 5hmC to 5-formylcytosine (5fC) and then 5- carboxylcytosine (5caC) in successive reactions.

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#Unit 13. Methods in Biology

The denser a biological structure is, the faster it sediments in a centrifugal field.

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#Unit 3. Fundamental Processes

significantly higher dissociation rate at 25C than at 37C, and a much higher dissociation rate at 15C. Because high temperature promotes DNA melting

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#Unit 4. Cell Communication and Cell Signaling

Chromosomal translocation 

That brings a growth regulatory gene under the control of alternative enhancers that cause inappropriate expression of the gene

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#Unit 8. Inheritance Biology

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#Unit 2. Cellular Organization

Most common CFTR mutation is a ΔF508 -

Prevents normal transport of CFTR to the plasma membrane by blocking its packaging into COPII vesicles budding from the ER. 

Change the conformation of the cytosolic portion of CFTR so that the signal is unable to bind to Sec24.