Tandem duplication - Duplicated chromosome segment is adjacent to the original segment.

TLS Online TPP Program

#Id: 3224

#Unit 3. Fundamental Processes

Xeroderma pigmentosum (XP) is a human disease caused by mutations in any one of several nucleotide excision repair genes.

TLS Online TPP Program

#Id: 3226

#Unit 3. Fundamental Processes

Numerous proteins, including XP products and the transcription factor TFnH, are involved in eukaryotic nucleotide excision repair. 

TLS Online TPP Program

#Id: 3228

#Unit 3. Fundamental Processes

Global genome repair recognizes damage anywhere in the genome.

TLS Online TPP Program

#Id: 3230

#Unit 3. Fundamental Processes

Transcriptionally active genes are preferentially repaired via transcription-coupled repair.

TLS Online TPP Program

#Id: 3233

#Unit 3. Fundamental Processes

Global genome repair and transcription-coupled repair differ in their mechanisms of damage recognition (XPC vs. RNA polymerase II).

TLS Online TPP Program

#Id: 3236

#Unit 3. Fundamental Processes

transitions, which are pyrimidine-to-pyrimidine and purine-to-purine substitutions, such as T to C and A to G;