Pointers

  1. Home
  2. Free Resources
  3. Pointers
  4. 6924
TLS Online TPP Program

#Id: 6924

Deletion includes the centromere, then the chromosome will not segregate in meiosis or mitosis and will usually be lost.


#Unit 8. Inheritance Biology #Structural and numerical alterations of chromosomes #Part B Pointers
PYQ Links
  1. PYQ 1
Extensive Links
  1. Link 1
More Pointers
TLS Online TPP Program

#Id: 10006

#Unit 4. Cell Communication and Cell Signaling

Hedgehog protein with autoproteolytic activity that cleaves off the C-terminus to reveal a signal sequence that marks the protein for secretion.
TLS Online TPP Program

#Id: 10007

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 10008

#Unit 4. Cell Communication and Cell Signaling

The freed C-terminal is not involved in signaling and is often degraded, whereas the N-terminal becomes the active Hedgehog protein intended for secretion
TLS Online TPP Program

#Id: 10009

#Unit 4. Cell Communication and Cell Signaling

Secretion requires the addition of cholesterol and palmitic acid to the Hedgehog protein
TLS Online TPP Program

#Id: 10010

#Unit 4. Cell Communication and Cell Signaling

Two membrane proteins, 
Smoothened (Smo) 
Patched (Ptc)
TLS Online TPP Program

#Id: 10011

#Unit 4. Cell Communication and Cell Signaling

Smo has seven TM α helices, is a member of the GPCR superfamily, and is related in sequence to the Fz.