1. DNA polymerase I is a single polypeptide of 103 kD. 

2. The chain can be cleaved into two parts by proteolytic treatment. The larger cleavage product (68 kD) is called the Klenow fragment. It is used in synthetic reactions in vitro. 

3. It contains the polymerase and the proofreading 3’–5’ exonuclease activities.

TLS Online TPP Program

#Id: 7766

#Unit 1. Molecules and their Interaction Relevant to Biology

Atoms are indivisible particles that can't be created or destroyed in a chemical reaction

TLS Online TPP Program

#Id: 5075

#Unit 6. System Physiology – Plant

Paál and Went experiment

TLS Online TPP Program

#Id: 8864

#Unit 2. Cellular Organization

Defects of cohesin’s gene expression regulation function are the cause of a group of diseases collectively called cohesinopathies.

TLS Online TPP Program

#Id: 3371

#Unit 3. Fundamental Processes

Structural studies show that the active site of DNA Pol h is better at accommodating a thymine dimer than is the active site of another translesion DNA polymerase (DNA Pol k

TLS Online TPP Program

#Id: 9669

#Unit 4. Cell Communication and Cell Signaling

PI-3 kinase was first identified in studies of the 

polyoma virus, a DNA virus