If a stem cell divides symmetrically, have the ability to produce either two stem cells (increasing the stem cell pool by one) or two committed cells (decreasing the pool by one). This is called symmetrical renewing or symmetrical differentiating.

TLS Online TPP Program

#Id: 8411

#Unit 2. Cellular Organization

In the absence of Ca2+, muscle is relaxed

TM blocks myosin’s interaction with F-actin

TLS Online TPP Program

#Id: 8412

#Unit 2. Cellular Organization

Binding of Ca2+ ions to TN-C

triggers movement of TM to a new position on the filament, thereby exposing the myosin-binding sites on actin.

TLS Online TPP Program

#Id: 8413

#Unit 2. Cellular Organization

Troponin C is closely related to the ubiquitous 

Ca2+-binding protein calmodulin

TLS Online TPP Program

#Id: 8414

#Unit 2. Cellular Organization

Familial hypertrophic cardiomyopathy

point mutations in cardiac β-myosin heavy chain gene mutations in other genes encoding contractile proteins including myosin light chains, cardiac troponin,

and tropomyosin. 

TLS Online TPP Program

#Id: 8415

#Unit 2. Cellular Organization

Dilated cardiomyopathy

Minor missense mutations in the cardiac actin gene

TLS Online TPP Program

#Id: 8513

#Unit 2. Cellular Organization