All tissue types possess a unique stem cell niche, and despite many differences among the niche architecture of different tissues.

TLS Online TPP Program

#Id: 5181

#Unit 7. System Physiology – Animal

Hemostasis is the process of forming clots in the walls of damaged blood vessels and preventing blood loss while maintaining blood in a fluid state within the vascular system.

TLS Online TPP Program

#Id: 5182

#Unit 7. System Physiology – Animal

During formation of a clot the initial event is constriction of the vessel and formation of a temporary hemostatic plug of platelets.

TLS Online TPP Program

#Id: 5183

#Unit 7. System Physiology – Animal

The vasoconstriction is due to serotonin, histamines & other vasoconstrictors liberated from platelets that adhere to the walls of the damaged vessels.

TLS Online TPP Program

#Id: 5184

#Unit 7. System Physiology – Animal

The loose aggregation of platelets in the temporary plug is bound together and converted into the definitive clot by fibrin.

TLS Online TPP Program

#Id: 5185

#Unit 7. System Physiology – Animal

Fibrin formation involves a cascade of enzymatic reactions and a series of numbered clotting factors.

TLS Online TPP Program

#Id: 5186

#Unit 7. System Physiology – Animal

The fundamental reaction is conversion of the soluble plasma protein fibrinogen to insoluble fibrin.