Unpaired protein activates the JAK-STAT pathway in the adjacent germ stem cells to specify their self-renewal

TLS Online TPP Program

#Id: 1856

#Unit 3. Fundamental Processes

Promoters that do not contain a TATA element are called TATA-less promoters. Surveys of promoter sequences suggest that 50% or more of promoters may be TATA-less.

TLS Online TPP Program

#Id: 1857

#Unit 3. Fundamental Processes

Constitutive active housekeeping genes and developmentally regulated genes have TATA-less promoters. 

 

TLS Online TPP Program

#Id: 1858

#Unit 3. Fundamental Processes

TATA less, Inr Less promoters uses Sp1 activator to position TBP with TAFs

TLS Online TPP Program

#Id: 1859

#Unit 3. Fundamental Processes

Sp1 (Mr  80,000) is a transcription activator for a large number of genes in higher eukaryotes. Its DNA binding site, the GC box consensus sequence GGGCGG.

TLS Online TPP Program

#Id: 1860

#Unit 3. Fundamental Processes

Sp1 contains three zinc fingers, 25% of their amino acid residues are Gln.

TLS Online TPP Program

#Id: 1861

#Unit 3. Fundamental Processes

RNA polymerase III transcribes a set of short genes. The classical class III genes (types I and II) have promoters that lie wholly within the genes.