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TLS Online TPP Program

#Id: 7038

Darwin’s evolutionary theory - Common descent


#Unit 11. Evolution and Behavior #Emergence of evolutionary thoughts #Part B Pointers
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TLS Online TPP Program

#Id: 3237

#Unit 4. Cell Communication and Cell Signaling

miR-15-a and miR-16-1 act like tumor-suppressors;
they normally inhibit B cell proliferation
TLS Online TPP Program

#Id: 3239

#Unit 4. Cell Communication and Cell Signaling

miR-21 targets tumor-suppressor gene PTEN phosphatase
TLS Online TPP Program

#Id: 10390

#Unit 4. Cell Communication and Cell Signaling

Four stages of the evolutionary progression of cancer:

Initiation→Cancer progression → Evasion of cancer cell elimination  → Tumor growth and dispersal 
TLS Online TPP Program

#Id: 10391

#Unit 4. Cell Communication and Cell Signaling

Cancer cells 
acquire a drive to proliferate 
does not require an external inducing signal
fail to sense signals that restrict cell division
survive when they should die
TLS Online TPP Program

#Id: 10392

#Unit 4. Cell Communication and Cell Signaling

Tumors are detected only after they have reached 1cm3 in size.
TLS Online TPP Program

#Id: 10393

#Unit 4. Cell Communication and Cell Signaling

Precancerous cells have: 
lost contact inhibition
less adherent and more rounded than normal cells
continue to divide