Nurturing Life Sciences
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#Unit 8. Inheritance Biology
Heterozygous condition may produce imbalances in the amounts of gene products similar to those produced by extra gene copies.
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Pseudodominance - Recessive allele owing to a deletion on the homologous chromosome.
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Haploinsufficiency - One copy of the gene is missing; a mutant phenotype is produced
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Deletions can be detected cytologically by studying the banding patterns in stained chromosomes.
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hCONDEL - Deletions within the human genome containing sequences that are highly conserved among closely related relatives.