TLS Online TPP Program

#Id: 2580

#Unit 7. System Physiology – Animal

Proximal tubule epithelial cells are highly metabolic and have large numbers of mitochondria to support

powerful active transport processes.

TLS Online TPP Program

#Id: 2581

#Unit 7. System Physiology – Animal

In early proximal convoluted tubule

sodium is reabsorbed by co-transport along with glucose, amino acids, & other solutes

TLS Online TPP Program

#Id: 2582

#Unit 7. System Physiology – Animal

Late proximal tubule reabsorbs primarily NaCl.

TLS Online TPP Program

#Id: 2583

#Unit 7. System Physiology – Animal

In late proximal convoluted tubule

High tubular fluid Cl− concentration is the driving

force for reabsorption

TLS Online TPP Program

#Id: 2584

#Unit 7. System Physiology – Animal

There are two components for Cl− reabsorption:

Transcellular

Paracellular

TLS Online TPP Program

#Id: 2585

#Unit 7. System Physiology – Animal

Function of the two exchangers is to transport NaCl from the lumen into the cell:

Na+-H+ exchanger

Cl−-formate− anion exchanger