The transition from specification to determination in Drosophila is mediated by Segmentation genes.

TLS Online TPP Program

#Id: 1103

#Unit 2. Cellular Organization

Na+–K+ ATPase, consists of two types of subunits: 

α2 subunit

β2 subunit

TLS Online TPP Program

#Id: 1104

#Unit 2. Cellular Organization

Transmembrane domain with the binding sites for transported ligand.

TLS Online TPP Program

#Id: 1105

#Unit 2. Cellular Organization

Phosphorylation domain contains the canonical Asp351 phosphorylated.

TLS Online TPP Program

#Id: 1106

#Unit 2. Cellular Organization

Nucleotide binding domain serves as a built-in protein kinase that functions to phosphorylate the P domain.

TLS Online TPP Program

#Id: 1107

#Unit 2. Cellular Organization

Actuator domain has protein phosphatase activity and removes the phosphoryl group from the Asp residue

TLS Online TPP Program

#Id: 1108

#Unit 2. Cellular Organization

E1’s ion-binding sites are exposed to the cytoplasm, and it has high affinity for Na+ but low affinity for K+