Neighboring cells respond to cAMP in two ways:

Initiate a movement toward the cAMP pulse for about a minute

Release cAMP of their own

TLS Online TPP Program

#Id: 7396

#Unit 5. Developmental Biology

Translated Gurken is received by Torpedo proteins. Torpedo signal causes follicle cells to differentiate to a dorsal morphology.

Gurken does not diffuse to ventral

follicle cells

TLS Online TPP Program

#Id: 7397

#Unit 5. Developmental Biology

Pipe synthesis is inhibited in dorsal follicle cells

TLS Online TPP Program

#Id: 7398

#Unit 5. Developmental Biology

Ventral follicle cells synthesize Pipe. Pipe signal sulfates ventral vitelline proteins

TLS Online TPP Program

#Id: 7399

#Unit 5. Developmental Biology

Sulfated vitelline membrane proteins bind Gastrulation-defective.

TLS Online TPP Program

#Id: 7400

#Unit 5. Developmental Biology

GD cleaves Snake to its active form and forms a complex with Snake and uncleaved Easter proteins.

Easter protein is cleaved into its

active form.

TLS Online TPP Program

#Id: 7401

#Unit 5. Developmental Biology

Cleaved Easter binds to and cleaves Spätzle; activated Spätzle binds to Toll receptor protein