free energy for this reaction is rather small (DG–3.5 kcal/mol).

TLS Online TPP Program

#Id: 3087

#Unit 3. Fundamental Processes

he gene ftsZ plays a central role in division. Mutations in ftsZ block septum formation and generate filaments.

TLS Online TPP Program

#Id: 3088

#Unit 3. Fundamental Processes

FtsZ functions at an early stage of septum formation. Early in the division cycle, FtsZ is localized throughout the cytoplasm, but prior to cell division.

TLS Online TPP Program

#Id: 3089

#Unit 3. Fundamental Processes

FtsZ is a GTPase that forms a ring on the inside of the bacterial envelope. It is connected to other cytoskeletal components.

TLS Online TPP Program

#Id: 3090

#Unit 3. Fundamental Processes

The structme of FtsZ resembles tubulin,

TLS Online TPP Program

#Id: 3091

#Unit 3. Fundamental Processes

wo other proteins needed for division, ZipA and FtsA.

TLS Online TPP Program

#Id: 3092

#Unit 3. Fundamental Processes

A fixed time of40 minutes is required to replicate the E. coli chromosome, and an additional 20 minutes is required before the cell can divide.